Just recently, I've been thinking of the situation in Newcastle and how the current set up doesn't lend itself to cross-city centre connections (for terminating services), without changing buses or potentially incurring additional costs.
Newcastle isn't the biggest city in the world, but for those getting off a service at Haymarket or Eldon Square, it can be a pain if you're needing to be on the other side of the town, at say Central Station or the College.
To get from either from Haymarket or Eldon Square, means walking, transferring bus or getting the metro for a few stops. Maybe even getting off at Gateshead for northbound services.
None are very practical if you're lugging around stuff ahead of a trip on an Intercity type of service, or are taking in to account any physical limitations or inclement weather.

Will the Blackett St closure lend itself to services looping around the town and essentially opening up new, improved direct connections? 
Short-term, would it be feasible for a terminating service such as the 21, to allow passengers from Low Fell to stay on board at Eldon Square and get off at the Castle Keep? 

Prior to the High Level being changed to southbound only, it was possible to choose a service from South of the river and get pretty close to Central and that part of the town. Clearly, that's not the case now.